Here, we show that conolidine, a purely natural analgesic alkaloid Utilized in traditional Chinese medicine, targets ACKR3, therefore offering added evidence of the correlation involving ACKR3 and pain modulation and opening alternative therapeutic avenues for that remedy of Continual suffering. We demonstrated that, in distinction to classical opioid receptors, https://what-is-chronic-pain04545.bluxeblog.com/63156994/the-2-minute-rule-for-what-is-conolidine