2. Histamine Receptor Antagonism: Some sedatives, including antihistamines, exert their sedative effects by blocking histamine receptors from the brain, notably H1 receptors. Histamine performs a task in wakefulness and arousal, so blocking its effects promotes sedation and sleepiness. Sufficient and perfectly-controlled reports have didn't show a hazard for the https://eduardoleujx.collectblogs.com/78081316/sedative-medications-in-icu-their-roles-effects