Epidural clonidine used as an adjunct to local anesthetics has three different mechanisms of action. Initially, the stimulation of alpha-2-receptors within the dorsal horn minimizes pain transmission. Secondly, clonidine could potentially cause area vasoconstriction that limits vascular removal of area epidural anesthetics. Clonidine is a lengthy-time period medication. It https://franzw849mdt4.wikiap.com/user