Background: Many plant secondary metabolites (PSMs) were shown to intercalate into DNA helix or interact with DNA grooves. This may influence histone-DNA interactions changeing chromatin structure and genome functioning. Methods: Nucleosome stability and linker histone H1. https://safeersappliancers.shop/product-category/neff-n70-t59ft50x0-electric-induction-hob-black/