Critically unwell patients: Nitrous oxide inactivates methionine synthase by way of oxidation in the cobalt in vitamin B12 and could produce megaloblastic anemia. This enzyme is important for vitamin B12 and folate metabolism and performs a task in DNA and RNA synthesis plus the synthesis of other substances. Otherwise taken https://beaukbqhw.iamthewiki.com/9097967/the_fact_about_nitrous_oxide_canisters_that_no_one_is_suggesting